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Anti-Kallikrein 15/KLK15 Antibody (2C545) is a Mouse antibody targeting Kallikrein 15/KLK15. Anti-Kallikrein 15/KLK15 Antibody (2C545) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-Kallikrein 15/KLK15 Antibody (2C545) is a Mouse antibody targeting Kallikrein 15/KLK15. Anti-Kallikrein 15/KLK15 Antibody (2C545) can be used in ELISA,IHC-P. |
Alias | kallikrein-related peptidase 15 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 2C545 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human KLF15 in human prostate with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human KLF15 in human stomach with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining of human KLF15 in human testis with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KLK15 (rh KLK15; TMPY-05289; NP_059979.2; Met1-Asn256). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | KLK15 (Kallikrein Related Peptidase 15) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Human KLK15 may have some utility as a prostate, ovarian, and breast cancer biomarker, based on previous studies, which examined mRNA levels of KLK15. Aberrant KLK15 expression is found in breast, ovarian, and prostate cancers. KLK15 over-expression is reported to be a significant predictor of reduced progression-free survival and overall survival in ovarian cancer. Kallikrein 15 (KLK15)/Prostinogen is a plausible candidate for prostate cancer susceptibility. Elevated KLK15 expression has been reported in prostate cancer and it has been described as an unfavorable prognostic marker for the disease. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human KLK15 Protein (TMPY-05289) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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