Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-HMOX1 Polyclonal Antibody is a Rabbit antibody targeting HMOX1. Anti-HMOX1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-HMOX1 Polyclonal Antibody is a Rabbit antibody targeting HMOX1. Anti-HMOX1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
Synonyms | HO-1, HO1, HO, HMOX1, Heme oxygenase 1 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat,Pig (predicted:Chicken,Dog,Cow,Horse,Rabbit,Sheep,GuineaPig) |
Verified Activity | 1. Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-Heme Oxygenase 1 Polyclonal Antibody, Unconjugated (TMAB-00875) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Sample: Lane 1: HepG2 (Human) Cell Lysate at 30 μg Lane 2: A549 (Human) Cell Lysate at 30 μg Lane 3: DU145 (Human) Cell Lysate at 30 μg Lane 4: H9C2 (Rat) Cell Lysate at 30 μg Lane 5: 293T (Human) Cell Lysate at 30 μg Primary: Anti-Heme Oxygenase 1 (TMAB-00875) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 35 kDa |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Microsome. Endoplasmic reticulum. |
Tissue Specificity | Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member. |
Immunogen | KLH conjugated synthetic peptide: human HO-1 |
Antigen Species | Human |
Gene Name | HMOX1 |
Gene ID | |
Protein Name | Heme oxygenase 1 |
Uniprot ID | |
Biology Area | Response to hypoxia,Inflammatory mediators,Platelets,Endothelium,NFkB pathway,Hypoxia,Cancer,Heart disease,Neurodegenerative disease,Alzheimer's disease,NFkB Pathway |
Function | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. |
Molecular Weight | Theoretical: 32 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.