B7-H5/VISTA Protein, Human, Recombinant (His)

Catalog No. TMPY-03219 Copy Product Info

VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.

B7-H5/VISTA Protein, Human, Recombinant (His)

Catalog No. TMPY-03219

Copy Product Info

VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.

B7-H5/VISTA Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$34	7-10 days	7-10 days
10 μg	$51	7-10 days	7-10 days
20 μg	$80	7-10 days	7-10 days
50 μg	$148	7-10 days	7-10 days
100 μg	$249	-	In Stock
200 μg	$442	7-10 days	7-10 days

Add to Cart

Add to Quotation

For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Biological Activity	Recombinant Human IGSF11 Protein (ECD, Fc Tag) captured on CM5 chip via Anti-Human IgG Fc, can bind Recombinant Human B7-H5 Protein (His Tag) with an affinity constant of 30.800 μM as determined in an SPR assay (Biacore 8K) (Routinely tested).
Description	VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	AAH20568.1
Synonyms	V-set immunoregulatory receptor,VISTA,SISP1,PP2135,PD-1H,GI24,DD1α,DD1alpha,C10orf54,B7-H5,B7H5
Construction	A DNA sequence encoding the human Gi24 (AAH20568.1) (Met1-Ala194) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Phe 33
Protein Purity	> 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC.
Molecular Weight	19.6 kDa (predicted); 38-42 kDa (reducing condition, due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8.