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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

🥰Excellent
Catalog No. T5065Cas No. 40732-48-7
Alias Monosodium-GMP, Cyclic GMP, cGMP sodium salt

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin. GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis.

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD
Other Forms of GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD:
Cyclic GMPTN90567665-99-8
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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

🥰Excellent
Purity: 99.53%
Catalog No. T5065Alias Monosodium-GMP, Cyclic GMP, cGMP sodium saltCas No. 40732-48-7
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin. GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis.
Pack SizePriceAvailabilityQuantity
10 mg$40In Stock
25 mg$68In Stock
50 mg$100In Stock
100 mg$147In Stock
200 mg$216In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.53%
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Product Introduction

Bioactivity
Description
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin. GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis.
SynonymsMonosodium-GMP, Cyclic GMP, cGMP sodium salt
Chemical Properties
Molecular Weight367.19
FormulaC10H11N5NaO7P
Cas No.40732-48-7
Smiles[Na+].Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 12 mg/mL (32.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7234 mL13.6169 mL27.2339 mL136.1693 mL
5 mM0.5447 mL2.7234 mL5.4468 mL27.2339 mL
10 mM0.2723 mL1.3617 mL2.7234 mL13.6169 mL
20 mM0.1362 mL0.6808 mL1.3617 mL6.8085 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

PKGGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODGUANOSINE 3':5'CYCLIC MONOPHOSPHATE SODGUANOSINE 3':5' CYCLIC MONOPHOSPHATE SODcGMP sodium
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