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Thiacloprid

Name: Thiacloprid
Brand: TargetMol
SKU: T38272
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T38272Cas No. 111988-49-9

Thiacloprid, a chloronicotinyl insecticide, acts as a selective agonist at insect nAChRs. The IC50 values are 2.7 and 860 nM for Drosophilan AChRs and M10 mouse fibroblast cells expressing α4β2 subunit-containing nAChRs, respectively.

Thiacloprid

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Purity: 99.95%

Catalog No. T38272Cas No. 111988-49-9

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$37	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.95%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Thiacloprid, a chloronicotinyl insecticide, acts as a selective agonist at insect nAChRs. The IC50 values are 2.7 and 860 nM for Drosophilan AChRs and M10 mouse fibroblast cells expressing α4β2 subunit-containing nAChRs, respectively.
Targets&IC50	α4β2 nAChR:2.7 nM(Drosophilan), α4β2 nAChR:860 nM(M10 mouse fibroblast cells)

Chemical Properties

Molecular Weight	252.72
Formula	C₁₀H₉ClN₄S
Cas No.	111988-49-9
Smiles	Clc1ccc(CN2CCS\C2=N/C#N)cn1
Relative Density.	1.424g/cm3

Storage & Solubility Information

Storage

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Methanol: Slightly soluble

DMSO: 255 mg/mL (1009.02 mM), Sonication is recommended.

Chloroform: Slightly soluble

In Vivo Formulation

10% DMSO+90% Corn Oil: 2.5 mg/mL (9.89 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9569 mL	19.7847 mL	39.5695 mL	197.8474 mL
5 mM	0.7914 mL	3.9569 mL	7.9139 mL	39.5695 mL
10 mM	0.3957 mL	1.9785 mL	3.9569 mL	19.7847 mL
20 mM	0.1978 mL	0.9892 mL	1.9785 mL	9.8924 mL
50 mM	0.0791 mL	0.3957 mL	0.7914 mL	3.9569 mL
100 mM	0.0396 mL	0.1978 mL	0.3957 mL	1.9785 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc