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immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]

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Catalog No. TP2259

Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. On each of the light chains, there is one variable region and a constant region. The variable region is the most important for binding to antigens.

immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]

immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]

😃Good
Catalog No. TP2259
Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. On each of the light chains, there is one variable region and a constant region. The variable region is the most important for binding to antigens.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50InquiryInquiry
5 mg$143InquiryInquiry
10 mg$235InquiryInquiry
25 mg$329InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. On each of the light chains, there is one variable region and a constant region. The variable region is the most important for binding to antigens.
In vitro
The antigen combining site of an antibody is made up of the variable regions of one light chain and one heavy chain. Within the variable regions, typically comprising 105-110 amino acids, some positions show more sequence variation than others. The variable fragments are the smallest fragment made from enzymatic cleavage of IgG and IgM class antibodies.
Chemical Properties
Molecular Weight1122.32
FormulaC54H83N13O13
SmilesNC(CC(C)C)C(NC(CC(C)C)C(NC(C(C)CC)C(NC(CC1=CC=C(O)C=C1)C(NC(CC2=CNC3=C2C=CC=C3)C(NC(C)C(NC(CO)C(NC(C(O)C)C(NC(CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Relative Density.no data available
SequenceH-DL-Leu-DL-Leu-DL-xiIle-DL-Tyr-DL-Trp-DL-Ala-DL-Ser-DL-xiThr-DL-Arg-OH
Sequence ShortLLYWASTR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: ≥112.2 mg/mL, Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]
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