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Anti-CD86 Antibody-PE (8R689) (Synonyms: LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2)

Catalog No. TMAY-01083P Copy Product Info
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Anti-CD86 Antibody-PE (8R689) is a PE-conjugated Mouse antibody targeting CD86. Anti-CD86 Antibody-PE (8R689) can be used in FCM.

Anti-CD86 Antibody-PE (8R689)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01083P
Synonyms LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2

Anti-CD86 Antibody-PE (8R689) is a PE-conjugated Mouse antibody targeting CD86. Anti-CD86 Antibody-PE (8R689) can be used in FCM.

Anti-CD86 Antibody-PE
(8R689)
Pack SizePriceUSA StockGlobal StockQuantity
25 T$807-10 days7-10 days
100 T$2587-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD86 Antibody-PE (8R689) is a PE-conjugated Mouse antibody targeting CD86. Anti-CD86 Antibody-PE (8R689) can be used in FCM.
SynonymsLAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Ig Type
Mouse IgG1
Clone
8R689
Reactivity
Human
Specificity
Human B7-2/CD86
Verified Activity
Profile of anti-B7-2 (CD86) reactivity on Daudi cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with 20 μg of human IgG/106 cells for 1 hour at 4 °C prior to staining, washed, then stained with PE Mouse anti-B7-2 (CD86).
Application
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD86 / B7-2 (rh CD86 / B7-2; TMPY-01180; NP_008820.2; Met 1-His 239) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundCD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/APC/PerCP/FITC
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Protein: Human CD86 / B7-2 protein (TMPY-01180)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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