Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | 1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1]. |
In vitro | 1-Isopropyltryptophan exhibits cytotoxicity against the murine DC 2.4 cell line with an IC50 value of 2.156 mM after 24 hours of exposure [1]. Furthermore, at a concentration of 100 µM for 48 hours, 1-Isopropyltryptophan reduces the expression of IDO-1 and IDO-2 mRNA in DC 2.4 cells stimulated by IFN-γ (0.5 µg/ml) [1]. |
Synonyms | 1-IsoPT |
Molecular Weight | 246.3 |
Formula | C14H18N2O2 |
CAS No. | 1219485-46-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
1-Isopropyltryptophan 1219485-46-7 Metabolism Indoleamine 2,3-Dioxygenase (IDO) 1-IsoPT inhibitor inhibit