IL-22 Protein, Human, Recombinant (HEK293)

Name: IL-22 Protein, Human, Recombinant (HEK293)
Brand: TargetMol
SKU: TMPS-00076
Rating: 4.5 (1 reviews)

(Synonyms: zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22, IL22, IL-21) Copy Product Info

Synonyms: zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22, IL22, IL-21

Catalog No. TMPS-00076 Copy Product Info

IL-22 Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is Q9GZX6.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$170	7-10 days	7-10 days
20 µg	$295	7-10 days	7-10 days
50 µg	$622	7-10 days	7-10 days
100 µg	$993	7-10 days	7-10 days
200 µg	$1,580	7-10 days	7-10 days
500 µg	$2,960	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The ED 50 for this effect is less than 0.3 ng/ml.
Description	IL-22 Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is Q9GZX6.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	Q9GZX6
Construction	Ala34-Ile179
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22, IL22, IL-21
Research Background	Interleukin-22(IL-22) belongs to a group of cytokines called the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26) which are a class of potent mediators of cellular inflammatory responses. It shares use of IL-10R2 in cell signaling with other members of this family, such as IL-10, IL-26, IL-28A/B and IL-29. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens in epithelial cells such as those in the lung and gut. IL-22 along with IL-17 is produced by splenic LTi-like cells and Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.

Chemical Properties

Molecular Weight

16~28 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.