Powder: -20°C for 3 years | In solvent: -80°C for 1 year
8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 μM, respectively. When infused into the renal artery of the rat at a concentration of 4 μg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 140.00 | |
1 mg | 35 days | $ 263.00 | |
5 mg | 35 days | $ 1,070.00 | |
10 mg | 35 days | $ 1,870.00 |
Description | 8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 μM, respectively. When infused into the renal artery of the rat at a concentration of 4 μg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure. |
Synonyms | 8-iso Prostaglandin E2 |
Molecular Weight | 352.47 |
Formula | C20H32O5 |
CAS No. | 27415-25-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): >5 mg/mL (from PGE2)
DMSO: >100 mg/mL (from PGE2)
Ethanol: >100 mg/mL (from PGE2)
DMF: >100 mg/mL (from PGE2)
You can also refer to dose conversion for different animals. More
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8-iso Prostaglandin E2 27415-25-4 8 iso Prostaglandin E2 8-iso Prostaglandin E-2 8iso Prostaglandin E2 inhibitor inhibit