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Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)

(Synonyms: T-cell surface antigen Leu-14, SIGLEC2FLJ22814, Siglec-2, sialic acid binding Ig-like lectin 2, CD22 molecule, CD22 antigenMGC130020, CD22, B-lymphocyte cell adhesion molecule, BL-CAM, B-cell receptor CD22) Copy Product Info

Synonyms: T-cell surface antigen Leu-14, SIGLEC2FLJ22814, Siglec-2, sialic acid binding Ig-like lectin 2, CD22 molecule, CD22 antigenMGC130020, CD22, B-lymphocyte cell adhesion molecule, BL-CAM, B-cell receptor CD22

Catalog No. TMPJ-00444 Copy Product Info
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$467-10 days7-10 days
10 µg$71-In Stock
20 µg$1137-10 days7-10 days
50 µg$2157-10 days7-10 days
100 µg$3977-10 days7-10 days
200 µg$7767-10 days7-10 days
500 µg$1,8307-10 days7-10 days
1 mg$2,7707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1.
Species
Mouse
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberAAA02562.1
Amino AcidSer22-Arg702
ConstructionSer22-Arg702
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsT-cell surface antigen Leu-14, SIGLEC2FLJ22814, Siglec-2, sialic acid binding Ig-like lectin 2, CD22 molecule, CD22 antigenMGC130020, CD22, B-lymphocyte cell adhesion molecule, BL-CAM, B-cell receptor CD22
Research Background
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or B-lymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec-2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec-2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.
Chemical Properties
Molecular Weight100-120 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) chemical structure | Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) molecular weight