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Anti-Phospho-IRF3 (Ser386) Antibody (1U230)
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Catalog No. TMAB-01435
Alias p-IRF3 (Ser386), p-IRF3 (S386), Phospho-IRF3 (S386), MGC94729, IRF3 (p-Ser386), IRF3 (p-S386), IRF 3, Interferon regulatory factor 3, IIAE7
Anti-Phospho-IRF3 (Ser386) Antibody (1U230) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (1U230) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Anti-Phospho-IRF3 (Ser386) Antibody (1U230)
Anti-Phospho-IRF3 (Ser386) Antibody (1U230)
😃Good
Catalog No. TMAB-01435Alias p-IRF3 (Ser386), p-IRF3 (S386), Phospho-IRF3 (S386), MGC94729, IRF3 (p-Ser386), IRF3 (p-S386), IRF 3, Interferon regulatory factor 3, IIAE7
Anti-Phospho-IRF3 (Ser386) Antibody (1U230) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (1U230) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μL | $153 | 7-10 days | |
| 50 μL | $273 | 7-10 days | |
| 100 μL | $488 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-IRF3 (Ser386) Antibody (1U230) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (1U230) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Alias | p-IRF3 (Ser386), p-IRF3 (S386), Phospho-IRF3 (S386), MGC94729, IRF3 (p-Ser386), IRF3 (p-S386), IRF 3, Interferon regulatory factor 3, IIAE7 |
| Ig Type | IgG |
| Clone | 1U230 |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep) |
| Verified Activity | MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (Phospho-IRF3 (S386)) monoclonal Antibody, Unconjugated (TMAB-01435) 1:50, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nucleus. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:50-200; ICC/IF: 1:50; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect. When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human IRF3 around the phosphorylation site of Ser386 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | SARS Coronavirus,TLR Signaling,Interferons,Other factors |
| Molecular Weight | Theoretical: 47 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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