Shopping Cart
Remove All
Your shopping cart is currently empty
IL12RB1 Protein, Human, Recombinant (aa 1-540, hFc)
(Synonyms: IMD30, IL-12R-BETA1, IL12RB, IL12R, CD212) Copy Product InfoSynonyms: IMD30, IL-12R-BETA1, IL12RB, IL12R, CD212
Catalog No. TMPY-07074 Copy Product Info
IL12RB1 Protein, Human, Recombinant (aa 1-540, hFc) is expressed in HEK293 Cells. The accession number is P42701-1.
Customer service consultation
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $68 | 7-10 days | 7-10 days | |
| 10 µg | $109 | 7-10 days | 7-10 days | |
| 20 µg | $172 | 7-10 days | 7-10 days | |
| 50 µg | $343 | 7-10 days | 7-10 days | |
| 100 µg | $682 | 7-10 days | 7-10 days | |
| 200 µg | $987 | 7-10 days | 7-10 days | |
| 500 µg | $2,200 | 7-10 days | 7-10 days | |
| 1 mg | $4,500 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Recombinant Human IL-23 (IL23A & IL12B Heterodimer) Protein (His Tag) at 2 μg/mL (100 μL/well) can bind IL12RB1 Protein, Human, Recombinant (aa 1-540, hFc) (Cat#TMPY-07074), the EC50 is 15-45 ng/mL. |
| Description | IL12RB1 Protein, Human, Recombinant (aa 1-540, hFc) is expressed in HEK293 Cells. The accession number is P42701-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P42701-1 |
| Construction | A DNA sequence encoding the Human IL12RB1 (NP_005526.1) (Met1-Glu540) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Protein Purity | ≥ 90% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Synonyms | IMD30, IL-12R-BETA1, IL12RB, IL12R, CD212 |
| Research Background | Interleukin 12 receptor, beta 1 is also known as IL-12 receptor beta component, IL-12R subunit beta-1, and CD212 antigen (CD212). IL12RB1(CD212) is a subunit of the interleukin 12 receptor. IL12RB1(CD212) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukin 12 (IL12) with a low affinity and is thought to be a part of the IL12 receptor complex. IL12RB1(CD212) forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of IL12RB1 and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. IL12RB1(CD212) Functions as an interleukin receptor that binds interleukin-12 with low affinity and is involved in IL12 transduction. It is associated with IL12RB2 it forms a functional, high-affinity receptor for IL12. IL12RB1(CD212) associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. |
| Molecular Weight | 84.13 kDa (predicted); 98.4 kDa (reducing contition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Recombinant Proteins
Preview
Related Tags: IL12RB1 Protein, Human, Recombinant (aa 1-540, hFc) chemical structure | IL12RB1 Protein, Human, Recombinant (aa 1-540, hFc) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.