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Anti-ADAM15 Antibody-PE (5X82)
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Catalog No. TMAY-00937P
Alias metargidin, MDC15, ADAM metallopeptidase domain 15
Anti-ADAM15 Antibody-PE (5X82) is a PE-conjugated Rabbit antibody targeting ADAM15. Anti-ADAM15 Antibody-PE (5X82) can be used in FCM.
Anti-ADAM15 Antibody-PE (5X82)
Anti-ADAM15 Antibody-PE (5X82)
😃Good
Catalog No. TMAY-00937PAlias metargidin, MDC15, ADAM metallopeptidase domain 15
Anti-ADAM15 Antibody-PE (5X82) is a PE-conjugated Rabbit antibody targeting ADAM15. Anti-ADAM15 Antibody-PE (5X82) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $128 | 7-10 days | |
| 100 T | $257 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Human |
| Alias | metargidin, MDC15, ADAM metallopeptidase domain 15 |
| Ig Type | Rabbit IgG |
| Clone | 5X82 |
| Reactivity | Human |
| Verified Activity | Profile of anti-ADAM15 reactivity on MCF-7 cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ADAM15 (rh ADAM15; TMPY-00961; NP_997074.1; Met 1-Thr 696) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Human ADAM15 protein (TMPY-00961) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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