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GRGDSP acetate(91037-75-1 free base)

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Catalog No. TP1290
Alias GRGDSP TFA

GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.

GRGDSP acetate(91037-75-1 free base)
Other Forms of GRGDSP acetate(91037-75-1 free base):

GRGDSP acetate(91037-75-1 free base)

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Purity: 99.77%
Catalog No. TP1290Alias GRGDSP TFA
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$33In StockIn Stock
5 mg$62In StockIn Stock
10 mg$110In StockIn Stock
25 mg$165In StockIn Stock
50 mg$247In StockIn Stock
100 mg$352In StockIn Stock
200 mg$488In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.77%
Appearance:Solid
Color:White
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COA HPLC MS

Product Introduction

Bioactivity
Description
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.
In vitro
As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) acetate can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) acetate is used as a soluble integrin-blocking RGD-based peptide. GRGDSP acetate is used widely together with other RGD peptides in integrin research. GRGDSP acetate can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization[2].
SynonymsGRGDSP TFA
Chemical Properties
Molecular Weight647.64
FormulaC24H41N9O12
SmilesCC(O)=O.O=C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N1[C@@H](CCC1)C(O)=O)=O)=O)=O)=O)CN
Relative Density.1.31g/cm3
SequenceGly-Arg-Gly-Asp-Ser-Pro
Sequence ShortGRGDSP
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 125 mg/mL (193.01 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.5441 mL7.7203 mL15.4407 mL77.2034 mL
5 mM0.3088 mL1.5441 mL3.0881 mL15.4407 mL
10 mM0.1544 mL0.7720 mL1.5441 mL7.7203 mL
20 mM0.0772 mL0.3860 mL0.7720 mL3.8602 mL
50 mM0.0309 mL0.1544 mL0.3088 mL1.5441 mL
100 mM0.0154 mL0.0772 mL0.1544 mL0.7720 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

IntegrinGRGDSP acetate(91037-75-1 free base)GRGDSP acetate(91037751 free base)GRGDSP acetate(91037 75 1 free base)
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