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Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.[1][2] Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of this AGE is catabolized before excretion.[3]
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $898 | Backorder | |
5 mg | $3,980 | Backorder | |
10 mg | $5,080 | Backorder |
Description | Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.[1][2] Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of this AGE is catabolized before excretion.[3] |
Molecular Weight | 378.433 |
Formula | C17H26N6O4 |
Cas No. | 124505-87-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | PBS (pH 7.2): 10 mg/mL (26.42 mM), Sonication is recommended. DMF: 21.4 mg/mL (56.55 mM), Sonication is recommended. Ethanol: 31.3 mg/mL (82.71 mM), Sonication is recommended. DMSO: 22.4 mg/mL (59.19 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMF/DMSO/Ethanol
DMF/DMSO/Ethanol
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