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Latent TGF beta 2 Protein, Mouse, Recombinant (His)
(Synonyms: transforming growth factor β2, transforming growth factor beta 2, Tgf-β2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, TGF β2, BB105277) Copy Product InfoSynonyms: transforming growth factor β2, transforming growth factor beta 2, Tgf-β2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, TGF β2, BB105277
Catalog No. TMPY-00413 Copy Product Info
Purity: 95.7%
TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $129 | 7-10 days | 7-10 days | |
| 10 µg | $212 | - | In Stock | |
| 20 µg | $343 | 7-10 days | 7-10 days | |
| 50 µg | $658 | 7-10 days | 7-10 days | |
| 100 µg | $1,080 | 7-10 days | 7-10 days | |
| 200 µg | $1,760 | 7-10 days | 7-10 days | |
| 500 µg | $3,380 | 7-10 days | 7-10 days | |
| 1 mg | $5,590 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.7%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | The whole mouse TGF beta 2 protein showed no activity. |
| Description | TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P27090 |
| Construction | A DNA sequence encoding the mouse Tgfb2 (NP_033393.2) (Met1-Ser414) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ser 20 |
| Protein Purity | > 90 % as determined by SDS-PAGE  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | transforming growth factor β2, transforming growth factor beta 2, Tgf-β2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, TGF β2, BB105277 |
| Research Background | TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, angiogenesis, and proliferation. TGF beta 2 suppression is a promising therapeutic approach for malignant tumor therapy. The signaling pathway of TGF beta 2/Smad plays an important role in the pathological process in posterior capsule opacification (PCO) after cataract surgery. Silencing Smad2 and Smad3 efficiently blocked the effect of TGF beta 2 on cell proliferation, migration, and extracellular matrix production. TGF beta 2 activation of MEKK3/ERK1/2/5 signaling modulates Has2 expression and hyaluronan (HA) production leading to the induction of epithelial to mesenchymal transformation (EMT) events. Besides, the upregulation of the TGF beta 2 level is a common pathological feature of Alzheimer's disease (AD) brains and suggests that it may be closely linked to the development of neuronal death related to AD. |
| Molecular Weight | 46.9 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Latent TGF beta 2 Protein, Mouse, Recombinant (His) chemical structure | Latent TGF beta 2 Protein, Mouse, Recombinant (His) molecular weight
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