Spaglumic acid acetate

Name: Spaglumic acid acetate
Brand: TargetMol
SKU: TQ0285L
Rating: 4.5 (1 reviews)

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Catalog No. TQ0285L

Alias Spaglumic acid acetate(3106-85-2 Free base), Isospaglumic acid acetate

Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.

Spaglumic acid acetate

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Catalog No. TQ0285LAlias Spaglumic acid acetate(3106-85-2 Free base), Isospaglumic acid acetate

Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.

Pack Size	Price	Availability
10 mg	$50	Backorder
25 mg	$89	Backorder
50 mg	$136	Backorder
100 mg	$197	Backorder
200 mg	$298	Backorder

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Product Introduction

Bioactivity

Description	Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.
In vitro	Spaglumic acid acetate is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic acid acetate is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of Spaglumic acid acetate and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1].
Synonyms	Spaglumic acid acetate(3106-85-2 Free base), Isospaglumic acid acetate

Chemical Properties

Molecular Weight	364.31
Formula	C₁₃H₂₀N₂O₁₀
Sequence	Ac-Asp-Glu-OH
Sequence Short	DE

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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