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Posaconazole Impurity 29

Name: Posaconazole Impurity 29
Brand: TargetMol
SKU: T64789
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T64789Cas No. 149809-43-8

Posaconazole Impurity 29 is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

Posaconazole Impurity 29

😃Good

Purity: 99.76%

Catalog No. T64789Cas No. 149809-43-8

Posaconazole Impurity 29 is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.76%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Posaconazole Impurity 29 is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

Chemical Properties

Molecular Weight	449.47
Formula	C₂₁H₂₁F₂N₃O₄S
Cas No.	149809-43-8
Smiles	Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1CO[C@](Cn2cncn2)(C1)c1ccc(F)cc1F

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (111.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2248 mL	11.1242 mL	22.2484 mL	111.2421 mL
5 mM	0.4450 mL	2.2248 mL	4.4497 mL	22.2484 mL
10 mM	0.2225 mL	1.1124 mL	2.2248 mL	11.1242 mL
20 mM	0.1112 mL	0.5562 mL	1.1124 mL	5.5621 mL
50 mM	0.0445 mL	0.2225 mL	0.4450 mL	2.2248 mL
100 mM	0.0222 mL	0.1112 mL	0.2225 mL	1.1124 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc