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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

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Catalog No. TP1963Cas No. 313988-89-5
Alias cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide, [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide

Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
Other Forms of [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide:
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFAT75913
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

😃Good
Catalog No. TP1963Alias cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide, [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic PolypeptideCas No. 313988-89-5
Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
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Product Introduction

Bioactivity
Description
Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
Targets&IC50
Y4 receptor (human):51 nM, Y1 receptor (human):530 nM, Y2 receptor (human):>500 nM, Y5 receptor (human):0.24 nM
Synonymscpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide, [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
Chemical Properties
Molecular Weight4207.67
FormulaC183H281N57O54S2
Cas No.313988-89-5
Relative Density.no data available
SequenceH-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2
Sequence ShortGPSQPTYPGDNATPEQMARYYSALRRYINMAXRQRY
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 1 mg/mL (0.24 mM), Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

[cPP-1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide[cPP17,NPY1923,Ala31,Aib32,Gln34]hPancreatic Polypeptide[cPP1 7,NPY19 23,Ala31,Aib32,Gln34] hPancreatic Polypeptide
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