Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 481.00 | |
10 mg | Inquiry | $ 698.00 | |
25 mg | Inquiry | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 770.00 |
Description | PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1]. |
In vitro | PROTACs facilitate the targeted degradation of proteins and polypeptides by binding to cereblon at one end and the target protein (RIP2 kinase) at the other, thereby bringing the target protein close to the E3-Ligase. This interaction forms a ternary complex that results in the polyubiquitination and subsequent degradation of the target protein[1]. |
Molecular Weight | 889.01 |
Formula | C43H48N6O11S2 |
CAS No. | 2089205-64-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (112.49 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PROTAC RIPK degrader-6 2089205-64-9 PROTAC RIPK degrader6 PROTAC RIPK degrader 6 inhibitor inhibit