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P18IN011

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Catalog No. T8576Cas No. 77408-67-4
Alias P18IN011 - CAS 77408-67-4 - Calbiochem

P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).

P18IN011

P18IN011

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Purity: 97.63%
Catalog No. T8576Alias P18IN011 - CAS 77408-67-4 - CalbiochemCas No. 77408-67-4
P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$80In StockIn Stock
5 mg$179In StockIn Stock
10 mg$272In StockIn Stock
25 mg$448In StockIn Stock
50 mg$630In StockIn Stock
100 mg$852In StockIn Stock
200 mg$1,130-In Stock
1 mL x 10 mM (in DMSO)$188In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.63%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
SynonymsP18IN011 - CAS 77408-67-4 - Calbiochem
Chemical Properties
Molecular Weight332.33
FormulaC15H12N2O5S
Cas No.77408-67-4
SmilesO(S(=O)(=O)C1=CC=C(NC(C)=O)C=C1)C=2C=3C(ON2)=CC=CC3
Relative Density.1.468g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (75.23 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0091 mL15.0453 mL30.0906 mL150.4529 mL
5 mM0.6018 mL3.0091 mL6.0181 mL30.0906 mL
10 mM0.3009 mL1.5045 mL3.0091 mL15.0453 mL
20 mM0.1505 mL0.7523 mL1.5045 mL7.5226 mL
50 mM0.0602 mL0.3009 mL0.6018 mL3.0091 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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