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Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2
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Catalog No. TMAB-01888
Alias TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 can be used in ELISA,WB.
Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2
Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2
😃Good
Catalog No. TMAB-01888Alias TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 can be used in ELISA,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 can be used in ELISA,WB. |
| Synonyms | TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
| Immunogen | KLH conjugated synthetic peptide: human CD71 |
| Antigen Species | Human |
| Gene Name | TFRC |
| Gene ID | |
| Protein Name | Transferrin receptor protein 1 |
| Uniprot ID | |
| Biology Area | Response to hypoxia,Serum Proteins,Non-lineage,Hypoxia,B Lymphocytic Lineage,T Lymphocytic Lineage,Erythrocytic Lineage,Surface Molecules |
| Function | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferring for an overlapping C-terminal binding site. |
| Molecular Weight | Theoretical: 74/85 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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