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Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 (Synonyms: TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71)

Catalog No. TMAB-01888 Copy Product Info
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Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 can be used in ELISA, WB.

Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-01888
Synonyms TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71

Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 can be used in ELISA, WB.

Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Polyclonal Antibody 2 can be used in ELISA, WB.
SynonymsTR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
Ig Type
IgG
Reactivity
(predicted:Human,Mouse,Rat)
Application
Recommended Dose
WB: 1:500-2000; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CD71
Antigen Species
Human
Gene Name
TFRC
Gene ID
Protein Name
Transferrin receptor protein 1
Uniprot ID
Biology Area
Response to hypoxia,Serum Proteins,Non-lineage,Hypoxia,B Lymphocytic Lineage,T Lymphocytic Lineage,Erythrocytic Lineage,Surface Molecules
Function
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferring for an overlapping C-terminal binding site.
Chemical Properties
Molecular WeightTheoretical: 74/85 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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