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Anti-DCPLA Antibody (2R679)
(Synonyms: Transcription factor SMIF, SMAD4IP1 SMIF, Smad4-interacting transcriptional co-activator, Smad4 interacting transcriptional co activator, Putative protein product of Nbla00360, Nbla00360, mRNA-decapping enzyme 1A, mRNA decapping enzyme 1A, HSA275986, Decapping mRNA 1A, Decapping enzyme hDcp1a, DCP1A_HUMAN, Dcp1a, DCP1 decapping enzyme homolog A) Copy Product Info
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Synonyms: Transcription factor SMIF, SMAD4IP1 SMIF, Smad4-interacting transcriptional co-activator, Smad4 interacting transcriptional co activator, Putative protein product of Nbla00360, Nbla00360, mRNA-decapping enzyme 1A, mRNA decapping enzyme 1A, HSA275986, Decapping mRNA 1A, Decapping enzyme hDcp1a, DCP1A_HUMAN, Dcp1a, DCP1 decapping enzyme homolog A
Catalog No. TMAC-01123 Copy Product Info
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Anti-DCPLA Antibody (2R679) is a Rabbit antibody targeting DCPLA. Anti-DCPLA Antibody (2R679) can be used in FCM,ICC,IHC,WB.
Anti-DCPLA Antibody
(2R679)
(2R679)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
Related Conjugates and Formulations
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| Description | Anti-DCPLA Antibody (2R679) is a Rabbit antibody targeting DCPLA. Anti-DCPLA Antibody (2R679) can be used in FCM,ICC,IHC,WB. |
| Synonyms | Transcription factor SMIF, SMAD4IP1 SMIF, Smad4-interacting transcriptional co-activator, Smad4 interacting transcriptional co activator, Putative protein product of Nbla00360, Nbla00360, mRNA-decapping enzyme 1A, mRNA decapping enzyme 1A, HSA275986, Decapping mRNA 1A, Decapping enzyme hDcp1a, DCP1A_HUMAN, Dcp1a, DCP1 decapping enzyme homolog A |
| Ig Type | IgG |
| Clone | 2R679 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cleavage of the 5'-cap structure is involved in the major 5'-to-3' and nonsense-mediated mRNA decay pathways. The protein complex consisting of Dcp1 and Dcp2 has been identified as the species responsible for the decapping reaction in Saccharomyces cerevisiae. In nonsense-mediated decay, the human decapping complex, made up of S. cerevisiae homologs Dcp1a and hDcp2, may be recruited to mRNAs containing premature termination codons by nonsense-mediated decay factor (Upf) proteins. hDcp2 specifically hydrolyzes methylated capped RNA to release m(7)GDP, thereby aiding in mRNA degradation. Both Dcp1a and hDcp2 colocalize in the cytoplasm. In addition, Dcp1a interacts with Smad4 forming a complex with TGFβ and BMP-4. Dcp1a and Smad4 interact directly through a EVH1/WH1 domain on Dcp1a and a proline-rich activation domain on Smad4. Smad4 is essential to nuclear translocation of Dcp1a as deletion of the Smad4-interacting domain (located in the N-terminal 100 amino acids) of Dcp1a eliminates TGFβ-induced nuclear translocation of Dcp1a. |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | Theoretical: 63 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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