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Gadopentetic acid

Name: Gadopentetic acid
Brand: TargetMol
SKU: T19332
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19332Cas No. 80529-93-7

Alias Gd-DTPA, gadolinium complex

Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.

Gadopentetic acid

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Catalog No. T19332Alias Gd-DTPA, gadolinium complexCas No. 80529-93-7

Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$31	In Stock	In Stock
100 mg	$41	In Stock	In Stock
500 mg	$89	In Stock	In Stock
1 g	$129	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.
In vivo	The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI.?[Gd-DTPA0] is related to the administered bolus dose and varies with subjects.?A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L.
Synonyms	Gd-DTPA, gadolinium complex

Chemical Properties

Molecular Weight	547.57
Formula	C₁₄H₂₀GdN₃O₁₀
Cas No.	80529-93-7
Smiles	O=C1[O-][Gd+3]23([O-]C4=O)([O-]C5=O)([O-]C6=O)([N](CC[N]3(C5)C6)(C1)CC[N]2(C7)C4)[O-]C7=O.[H+].[H+]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (182.63 mM), Sonication is recommended.

DMSO: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8263 mL	9.1313 mL	18.2625 mL	91.3125 mL
5 mM	0.3653 mL	1.8263 mL	3.6525 mL	18.2625 mL
10 mM	0.1826 mL	0.9131 mL	1.8263 mL	9.1313 mL
20 mM	0.0913 mL	0.4566 mL	0.9131 mL	4.5656 mL
50 mM	0.0365 mL	0.1826 mL	0.3653 mL	1.8263 mL
100 mM	0.0183 mL	0.0913 mL	0.1826 mL	0.9131 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc