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MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated

(Synonyms: sMap, MASP-2, MASP1P1, MAP19) Copy Product Info

Synonyms: sMap, MASP-2, MASP1P1, MAP19

Catalog No. TMPK-00582 Copy Product Info
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1687-10 days7-10 days
20 µg$2797-10 days7-10 days
50 µg$5527-10 days7-10 days
100 µg$9327-10 days7-10 days
200 µg$1,6807-10 days7-10 days
500 µg$3,7207-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Anti-MASP2 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Rat MASP2, His Tag with the EC50 of 19.3ng/ml determined by ELISA.
Description
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
Species
Rat
Expression System
E. coli
TagC-His
Accession NumberA2VCV7
ConstructionThr287-Phe685
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 50 mM Tris, 200 mM NaCl (pH 9.0).
SynonymssMap, MASP-2, MASP1P1, MAP19
Research Background
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.
Chemical Properties
Molecular Weight46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated chemical structure | MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated molecular weight