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Anti-Marapsin Antibody (8D452)
😃Good
Catalog No. TMAY-02242
Alias UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2
Anti-Marapsin Antibody (8D452) is a Mouse antibody targeting Marapsin. Anti-Marapsin Antibody (8D452) can be used in ELISA.
Anti-Marapsin Antibody (8D452)
Anti-Marapsin Antibody (8D452)
😃Good
Catalog No. TMAY-02242Alias UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2
Anti-Marapsin Antibody (8D452) is a Mouse antibody targeting Marapsin. Anti-Marapsin Antibody (8D452) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Marapsin Antibody (8D452) is a Mouse antibody targeting Marapsin. Anti-Marapsin Antibody (8D452) can be used in ELISA. |
| Alias | UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8D452 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Pancreasin / Marapsin / PRSS27 (rh Pancreasin / Marapsin / PRSS27; TMPY-02117; Q9BQR3; Met1-Lys290). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most strongly up-regulated protease in psoriatic lesions, where expression was localized to the upper region of the hyperplastic epidermis. Similarly, in the hyperproliferative epithelium of regenerating murine skin wounds, marapsin localized to the suprabasal layers, where keratinocytes undergo squamous differentiation. Marapsin's restricted expression, localization, and cytokine-inducible expression suggest a role in the terminal differentiation of keratinocytes in hyperproliferating squamous epithelia. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Pancreasin / Marapsin / PRSS27 protein (TMPY-02117) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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