BTN2A2 Protein, Human, Recombinant (hFc)

Name: BTN2A2 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-01247
Rating: 4.5 (1 reviews)

(Synonyms: Butyrophilin subfamily 2 member A2, BTN2A2) Copy Product Info

Synonyms: Butyrophilin subfamily 2 member A2, BTN2A2

Catalog No. TMPJ-01247 Copy Product Info

BTN2A2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-80 KDa and the accession number is Q8WVV5.

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	7-10 days	7-10 days
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$791	7-10 days	7-10 days
200 µg	$1,180	7-10 days	7-10 days
500 µg	$2,030	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	BTN2A2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-80 KDa and the accession number is Q8WVV5.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q8WVV5
Amino Acid	Gln33-Val237
Construction	Gln33-Val237
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Butyrophilin subfamily 2 member A2, BTN2A2
Research Background	Butyrophilin 2A2 (BTN2A2) is a widely expressed type I transmembrane glycoprotein that functions as a negative regulator of immune responses. Mature human Butyrophilin 2A2 consisits of a 233 amino acid (aa) extracellular domain with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 237 aa cytoplasmic domain. Alternative splicing generates additional isoforms of human Butyrophilin 2A2 that lack the first, second, or both Iglike domains as well as isoforms with substitutions and deletions in the cytoplasmic region. Within the immune system, Butyrophilin 2A2 is expressed on thymic epithelial cells, naïve B cells, splenic NK cells, dendritic cells, and peritoneal macrophages and is up-regulated with cell activation. Butyrophilin 2A2 inhibits T cell proliferation and activation and enhances the development of FoxP3+ regulatory T cells. Its up-regulation in the hippocampus is associated with schizophrenia.

Chemical Properties

Molecular Weight

55-80 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.