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CYP1B1-IN-1

🥰Excellent
Catalog No. T60723Cas No. 842122-33-2

CYP1B1-IN-1 is a selective and highly potent cytochrome P450 1B1 (CYP1B1) inhibitor with potential anticancer and antitumor activity for breast cancer research.

CYP1B1-IN-1

CYP1B1-IN-1

🥰Excellent
Purity: 99.87%
Catalog No. T60723Cas No. 842122-33-2
CYP1B1-IN-1 is a selective and highly potent cytochrome P450 1B1 (CYP1B1) inhibitor with potential anticancer and antitumor activity for breast cancer research.
Pack SizePriceAvailabilityQuantity
1 mg$462In Stock
5 mg$1,070In Stock
10 mg$1,430In Stock
25 mg$2,130In Stock
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Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.87%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
CYP1B1-IN-1 is a selective and highly potent cytochrome P450 1B1 (CYP1B1) inhibitor with potential anticancer and antitumor activity for breast cancer research.
Targets&IC50
CYP1A1:5.2 nM, CYP1B1:0.49 nM, CYP1A2:73.6 nM
Chemical Properties
Molecular Weight306.74
FormulaC19H11ClO2
Cas No.842122-33-2
SmilesO=C1C=C(OC2=C1C=CC=3C=CC=CC32)C=4C=CC=C(Cl)C4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (254.27 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2601 mL16.3004 mL32.6009 mL163.0045 mL
5 mM0.6520 mL3.2601 mL6.5202 mL32.6009 mL
10 mM0.3260 mL1.6300 mL3.2601 mL16.3004 mL
20 mM0.1630 mL0.8150 mL1.6300 mL8.1502 mL
50 mM0.0652 mL0.3260 mL0.6520 mL3.2601 mL
100 mM0.0326 mL0.1630 mL0.3260 mL1.6300 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CYP1B1
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