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12-Epinapelline

Name: 12-Epinapelline
Brand: TargetMol
SKU: T4S1869
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4S1869Cas No. 110064-71-6

12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ channels are responsible for these observations.

12-Epinapelline

🥰Excellent

Purity: 99.89%

Catalog No. T4S1869Cas No. 110064-71-6

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$89	In Stock
10 mg	$136	In Stock
25 mg	$239	In Stock
50 mg	$355	In Stock
100 mg	$526	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	359.5
Formula	C₂₂H₃₃NO₃
Cas No.	110064-71-6
Smiles	[H][C@]12C[C@@]3(C4C[C@@]5([H])C6(C4N(CC)C[C@]5(C)CC[C@@H]6O)[C@]3([H])C[C@H]1O)[C@H](O)C2=C
Relative Density.	1.29 g/cm3 at 20℃

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (139.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7816 mL	13.9082 mL	27.8164 mL	139.0821 mL
5 mM	0.5563 mL	2.7816 mL	5.5633 mL	27.8164 mL
10 mM	0.2782 mL	1.3908 mL	2.7816 mL	13.9082 mL
20 mM	0.1391 mL	0.6954 mL	1.3908 mL	6.9541 mL
50 mM	0.0556 mL	0.2782 mL	0.5563 mL	2.7816 mL
100 mM	0.0278 mL	0.1391 mL	0.2782 mL	1.3908 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc