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Anti-DIO2 Polyclonal Antibody
(Synonyms: Type II iodothyronine deiodinase, Type II 5' deiodinase, Type 2 DI, TXDI2, Thyroxine deiodinase, type II, SelY, ITDI2, DIOII, Deiodinase, iodothyronine, type II, D2, 5DII) Copy Product Info
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Synonyms: Type II iodothyronine deiodinase, Type II 5' deiodinase, Type 2 DI, TXDI2, Thyroxine deiodinase, type II, SelY, ITDI2, DIOII, Deiodinase, iodothyronine, type II, D2, 5DII
Catalog No. TMAB-00548 Copy Product Info
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Anti-DIO2 Polyclonal Antibody is a Rabbit antibody targeting KCNN4. Anti-DIO2 Polyclonal Antibody can be used in IHC-P,IHC-F,IF.
Anti-DIO2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-DIO2 Polyclonal Antibody is a Rabbit antibody targeting KCNN4. Anti-DIO2 Polyclonal Antibody can be used in IHC-P,IHC-F,IF. |
| Synonyms | Type II iodothyronine deiodinase, Type II 5' deiodinase, Type 2 DI, TXDI2, Thyroxine deiodinase, type II, SelY, ITDI2, DIOII, Deiodinase, iodothyronine, type II, D2, 5DII |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass membrane protein (Potential). |
| Tissue Specificity | Heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms. |
| Immunogen | KLH conjugated synthetic peptide: human DIO2 |
| Antigen Species | Human |
| Gene Name | DIO2 |
| Gene ID | |
| Protein Name | Type II iodothyronine deiodinase |
| Uniprot ID | |
| Biology Area | Hormone biosynthesis,Hormone biosynthesis,Cancer,Thyroid axis,Hormones |
| Function | Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development. |
| Molecular Weight | Theoretical: 30 kDa. Actual: 30 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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