Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 394.00 | |
500 μg | 5 days | $ 1,570.00 | |
1 mg | 5 days | $ 2,640.00 |
Description | Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner. |
Species | Mouse |
Expression System | HEK293 |
Tag | N-hFc |
Accession Number | P12032 |
Synonyms | TPA-S1, CLGI, TIMP-1, EPO, TIMP, EPA, EPATIMP-1, TPAS1 |
Construction | Recombinant Mouse TIMP1 Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Cys25-Arg205.[Accession |P12032] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 46.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner. |
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Please read the User Guide of Recombinant Proteins for more specific information.
TIMP-1 Protein, Mouse, Recombinant (hFc) TPA-S1 CLGI TIMP-1 EPO EPATIMP1 TIMP1 TPAS 1 EPATIMP 1 TIMP 1 TIMP TPAS-1 EPA EPATIMP-1 TPAS1 recombinant recombinant-proteins proteins protein