The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited number of cancers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 465.00 | |
500 μg | 5 days | $ 1,850.00 | |
1 mg | 5 days | $ 3,100.00 |
Description | The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited number of cancers. |
Species | Mouse |
Expression System | HEK293 |
Tag | N-hFc |
Accession Number | P30882 |
Synonyms | D17S136E, RANTES, SCYA5, SIS-δ, Ccl5, SISd, eoCP, MuRantes, TCP228, SIS-delta |
Construction | Recombinant Mouse CCL5 Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Ser24-Ser91.[Accession |P30882] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 35.2 kDa. Due to glycosylation, the protein migrates to 40-45 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited number of cancers. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CCL5 Protein, Mouse, Recombinant (hFc) D17S136E RANTES SCYA 5 SCYA5 SIS-δ Ccl5 SISd eoCP TCP 228 SCYA-5 MuRantes TCP228 TCP-228 SIS-delta recombinant recombinant-proteins proteins protein