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N6-Methyladenosine 5'-monophosphate disodium salt

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Catalog No. T12162Cas No. 81921-35-9

N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.

N6-Methyladenosine 5'-monophosphate disodium salt

N6-Methyladenosine 5'-monophosphate disodium salt

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Purity: 99.36%
Catalog No. T12162Cas No. 81921-35-9
N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$95-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.36%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.
Targets&IC50
Glycogen phosphorylase b:22 µM (Ka)
In vitro
N6-Methyladenosine 5'-monophosphate disodium salt is an inhibitor of non-competitive rat adenylate kinase II. [1]
N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b ( Ka =22 µM). [2]
Chemical Properties
Molecular Weight405.21
FormulaC11H14N5Na2O7P
Cas No.81921-35-9
SmilesO[C@H]1[C@@H](O[C@@H]([C@H]1O)COP([O-])([O-])=O)N2C3=NC=NC(NC)=C3N=C2.[Na+].[Na+]
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20 mg/mL (49.36 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.4679 mL12.3393 mL24.6786 mL123.3928 mL
5 mM0.4936 mL2.4679 mL4.9357 mL24.6786 mL
10 mM0.2468 mL1.2339 mL2.4679 mL12.3393 mL
20 mM0.1234 mL0.6170 mL1.2339 mL6.1696 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N6Methyladenosine 5'monophosphate disodium saltN-6-Methyladenosine 5'-monophosphate disodium saltN6-Methyladenosine 5'-monophosphate disodiumN6-Methyladenosine 5'-monophosphateN6 Methyladenosine 5' monophosphate disodium saltGlycogen phosphorylase (GP)ADK
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