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L-Pyroglutamic acid

Name: L-Pyroglutamic acid
Brand: TargetMol
SKU: T0507
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0507Cas No. 98-79-3

Alias pidolic acid, L-pyroglutamate, 5-Oxoproline

L-Pyroglutamic acid (pidolic acid), a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism.

L-Pyroglutamic acid

🥰Excellent

Purity: 99.94%

Catalog No. T0507Alias pidolic acid, L-pyroglutamate, 5-OxoprolineCas No. 98-79-3

L-Pyroglutamic acid (pidolic acid), a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock

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Batch Information

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Purity:99.94%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	L-Pyroglutamic acid (pidolic acid), a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism.
Synonyms	pidolic acid, L-pyroglutamate, 5-Oxoproline

Chemical Properties

Molecular Weight	129.11
Formula	C₅H₇NO₃
Cas No.	98-79-3
Smiles	C(O)(=O)[C@H]1NC(=O)CC1
Relative Density.	1.38 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 201.4 mM, Sonication is recommended.

DMSO: 55 mg/mL (425.99 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (15.49 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	7.7453 mL	38.7267 mL	77.4533 mL	387.2667 mL
5 mM	1.5491 mL	7.7453 mL	15.4907 mL	77.4533 mL
10 mM	0.7745 mL	3.8727 mL	7.7453 mL	38.7267 mL
20 mM	0.3873 mL	1.9363 mL	3.8727 mL	19.3633 mL
50 mM	0.1549 mL	0.7745 mL	1.5491 mL	7.7453 mL
100 mM	0.0775 mL	0.3873 mL	0.7745 mL	3.8727 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc