The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 231.00 | |
50 μg | 5 days | $ 511.00 | |
500 μg | 5 days | $ 3,720.00 | |
1 mg | 5 days | $ 5,590.00 |
Description | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
Species | SARS-CoV-2 |
Expression System | E. coli |
Tag | Tag Free |
Accession Number | P0DTC1 |
Synonyms | M Proteinase, 3C-like Proteinase, 3CL Proteinase |
Amino Acid | Ser3264-Gln3569 |
Construction | Recombinant SARS-CoV-2 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser3264-Gln3569 is expressed. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 30 kDa, reducing conditions |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Formulation | Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM EDTA, pH7.3. |
Stability & Storage |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Shipping |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Research Background | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
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Please read the User Guide of Recombinant Proteins for more specific information.
3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant M Proteinase 3C-like Proteinase 3CL Proteinase recombinant recombinant-proteins proteins protein