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Anti-Phospho-CDKN1B (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDKN1B (Thr198). Anti-Phospho-CDKN1B (Thr198) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-CDKN1B (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDKN1B (Thr198). Anti-Phospho-CDKN1B (Thr198) Polyclonal Antibody can be used in WB. |
| Synonyms | p-CDKN1B (Thr198), p-CDKN1B (T198), CDKN1B (p-Thr198), CDKN1B (p-T198) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western Blot analysis of VEC cells using Phospho-p27 (T198) Polyclonal Antibody. 2. Western blot analysis of lysates from HeLa cells, HepG2 cells and COLO cells, using p27 Kip1 (Phospho-Thr198) Antibody. The lane on the right is blocked with the phospho peptide. ![]() ![]() |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Threonine 198 (R-R-R(p)-Q-T) derived from Human p27 Kip1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 27 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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