Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PluriSIn #2 acts as a selective transcriptional inhibitor of topoisomerase II α (TOP2A) and effectively eliminates undifferentiated human pluripotent stem cells (hPSCs)[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 854.00 | |
50 mg | 6-8 weeks | $ 1,110.00 | |
100 mg | 6-8 weeks | $ 1,610.00 |
Description | PluriSIn #2 acts as a selective transcriptional inhibitor of topoisomerase II α (TOP2A) and effectively eliminates undifferentiated human pluripotent stem cells (hPSCs)[1]. |
In vitro | PluriSIn #2 (20 μM; 12 hours) treatment reduces TOP2A expression at the protein level[1].A 24h exposure of PluriSIn #2 (20 μM) is sufficient to induce massive cell death in hPSCs, but doesn't affect the viability of various other cell types derived from them[1]. Western Blot Analysis[1]Cell Line: B153 and HUES9 human pluripotent stem cells (hPSCs) |
Molecular Weight | 249.2 |
Formula | C11H8FN3O3 |
CAS No. | 56563-17-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (20.06 mM)
You can also refer to dose conversion for different animals. More
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PluriSIn #2 56563-17-8 inhibitor inhibit