Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 can block the cell cycle in G2 phase and induce apoptosis. HDAC-IN-46 can be used in triple negative breast cancer (TNBC) studies.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 2,140.00 | |
50 mg | 8-10 weeks | $ 2,785.00 | |
100 mg | 8-10 weeks | $ 3,520.00 |
Description | HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 can block the cell cycle in G2 phase and induce apoptosis. HDAC-IN-46 can be used in triple negative breast cancer (TNBC) studies. |
Molecular Weight | 438.53 |
Formula | C22H30N8O2 |
CAS No. | 2562386-85-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HDAC-IN-46 2562386-85-8 inhibitor inhibit