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Anti-DIAPH1 Antibody (6T639)

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Catalog No. TMAC-01148

Anti-DIAPH1 Antibody (6T639) is a Rabbit antibody targeting DIAPH1. Anti-DIAPH1 Antibody (6T639) can be used in WB,ICC,IF,IHC.

Anti-DIAPH1 Antibody (6T639)

Anti-DIAPH1 Antibody (6T639)

😃Good
Catalog No. TMAC-01148
Anti-DIAPH1 Antibody (6T639) is a Rabbit antibody targeting DIAPH1. Anti-DIAPH1 Antibody (6T639) can be used in WB,ICC,IF,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-DIAPH1 Antibody (6T639) is a Rabbit antibody targeting DIAPH1. Anti-DIAPH1 Antibody (6T639) can be used in WB,ICC,IF,IHC.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:5000-10000; IHC: 1:50-100; ICC: 1:50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundDia 1, also known as DIAPH1 (diaphanous homolog 1) or DRF1, a mammalian homolog of the Drosophila diaphanous gene, belongs to a family of formin homology (FH) proteins which are characterized by having tandemly aligned FH1 (formin homology 1) and FH2 (formin homology 2) domains in their carboxy terminal regions. Dia 1 contains a DAD (diaphanous autoregulatory) domain, which is involved in the elongation of actin filaments, and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain, which interacts with the DAD domain via autoinhibitory interactions to regulate the activation of Dia 1. Dia 1 is required for the assembly of F-actin structures, and regulates the polymerization and depolymerization of actin filaments. Localizing to the cell membrane, Dia 1 is expressed in a wide range of tissues, including brain, heart, lung and kidney. Defects to the gene encoding Dia 1 have been linked to deafness autosomal dominant type 1 (DFNA1), a disorder characterized by sensorineural hearing loss..
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: N-terminal human DIAPH1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 141 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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