Shopping Cart

Your shopping cart is currently empty

(E)-[6]-Dehydroparadol

Name: (E)-[6]-Dehydroparadol
Brand: TargetMol
SKU: T13436
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T13436Cas No. 878006-06-5

Alias (6)-Dehydroparadol

(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.

(E)-[6]-Dehydroparadol

🥰Excellent

Purity: 99.85%

Catalog No. T13436Alias (6)-DehydroparadolCas No. 878006-06-5

(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$31	In Stock	In Stock
5 mg	$51	In Stock	In Stock
10 mg	$71	In Stock	In Stock
25 mg	$131	In Stock	In Stock
50 mg	$178	In Stock	In Stock
100 mg	$257	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$56	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.85%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.
Targets&IC50	HCT116 cells:41.59 μM , HCT116 cells:43.02 μM
In vitro	(E)-[6]-Dehydroparadol (5-80 µM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 µM, respectively. (E)-[6]-Dehydroparadol (10-40 µM; 24 h) induces apoptosis in HCT-116 and H-1299 cells[1].
In vivo	(E)-[6]-Dehydroparadol at a concentration of 5 µM for 24 hours increases the fluorescence signal of Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] in Tg(gstp1:GFP) transgenic zebrafish embryos.
Synonyms	(6)-Dehydroparadol

Chemical Properties

Molecular Weight	276.37
Formula	C₁₇H₂₄O₃
Cas No.	878006-06-5
Smiles	CCCCCCCC(=O)\C=C\c1ccc(O)c(OC)c1
Relative Density.	1.040 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (434.2 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (14.47 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6183 mL	18.0917 mL	36.1834 mL	180.9169 mL
5 mM	0.7237 mL	3.6183 mL	7.2367 mL	36.1834 mL
10 mM	0.3618 mL	1.8092 mL	3.6183 mL	18.0917 mL
20 mM	0.1809 mL	0.9046 mL	1.8092 mL	9.0458 mL
50 mM	0.0724 mL	0.3618 mL	0.7237 mL	3.6183 mL
100 mM	0.0362 mL	0.1809 mL	0.3618 mL	1.8092 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc