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Anti-5T4/TPBG Antibody (8L405) is an antibody targeting 5T4/TPBG. Anti-5T4/TPBG Antibody (8L405) can be used in ELISA,IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-5T4/TPBG Antibody (8L405) is an antibody targeting 5T4/TPBG. Anti-5T4/TPBG Antibody (8L405) can be used in ELISA,IHC. |
| Synonyms | WAIF1, TPBG, M6P1, 5T4AG, 5T4 |
| Ig Type | Rabbit IgG |
| Clone | 8L405 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-01206 diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human 5T4 |
| Antigen Species | Human |
| Gene Name | TPBG |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Developmental biology, Immunology, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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