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Tiamulin fumarate

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Catalog No. T35346Cas No. 55297-96-6
Alias Tiamulin fumarate

Tiamulin fumarate (Thiamutilin fumarate) is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis.

Tiamulin fumarate
Other Forms of Tiamulin fumarate:

Tiamulin fumarate

🥰Excellent
Purity: 99.64%
Catalog No. T35346Alias Tiamulin fumarateCas No. 55297-96-6
Tiamulin fumarate (Thiamutilin fumarate) is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mgInquiryIn StockIn Stock
100 mg$34In StockIn Stock
500 mg$75In StockIn Stock
1 g$108In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.64%
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Product Introduction

Bioactivity
Description
Tiamulin fumarate (Thiamutilin fumarate) is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis.
In vitro
Tiamulin exhibits high activity against mycoplasma strains (Gloss M. gallisepticum, M. synoviae, M. meleagridis, and M. iowae), spirochetes (Brachyspira hyodysenteriae, Brachyspira innocens, B. pilosicoli, B. intermedia), and Gram-positive bacteria (Staphylococcus, Streptococcus, Clostridium, and Campylobacter spp), but its activity against Gram-negative bacteria (Bordetella, Klebsiella, Haemophilus, Clostridium, Campylobacter, and Corynebacterium spp) is relatively low[1].
In vivo
Tiamulin is highly effective in treating swine dysentery in both breeding and laying hens, with significant efficacy against B. pilosicoli and B. intermedia at a dose of 25 mg/kg body weight per day for 5 consecutive days [1].
SynonymsTiamulin fumarate
Chemical Properties
Molecular Weight609.81
FormulaC32H51NO8S
Cas No.55297-96-6
SmilesOC(=O)\C=C\C(O)=O.[H][C@@]12C(=O)CC[C@]11CC[C@@H](C)[C@@]2(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]1C)OC(=O)CSCCN(CC)CC
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (131.19 mM), Sonication is recommended.
DMSO: 80 mg/mL (131.19 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.6399 mL8.1993 mL16.3986 mL81.9928 mL
5 mM0.3280 mL1.6399 mL3.2797 mL16.3986 mL
10 mM0.1640 mL0.8199 mL1.6399 mL8.1993 mL
20 mM0.0820 mL0.4100 mL0.8199 mL4.0996 mL
50 mM0.0328 mL0.1640 mL0.3280 mL1.6399 mL
100 mM0.0164 mL0.0820 mL0.1640 mL0.8199 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Antibacterial
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