Shopping Cart
Remove All
Your shopping cart is currently empty
MDP1 acetate
Copy Product Info
🥰Excellent
Synonyms:
Catalog No. T76219L Copy Product Info
Purity: 99.52%
🥰Excellent
MDP1 acetate, a derivative of Melittin, compromises membrane integrity of both Gram-positive and Gram-negative bacteria leading to bacterial death through membrane damage. MDP1 acetate exhibits antibacterial activity against multidrug-resistant and reference strains of S. aureus, E. coli, and P. aeruginosa. MDP1 acetate is used in antimicrobial membrane biology research systems to investigate peptide-induced membrane disruption, bacterial permeability changes, and antimicrobial peptide mechanism profiling.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $48 | - | In Stock | |
| 5 mg | $113 | - | In Stock | |
| 10 mg | $185 | - | In Stock | |
| 25 mg | $372 | - | In Stock | |
| 50 mg | $596 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:99.52%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | MDP1 acetate, a derivative of Melittin, compromises membrane integrity of both Gram-positive and Gram-negative bacteria leading to bacterial death through membrane damage. MDP1 acetate exhibits antibacterial activity against multidrug-resistant and reference strains of S. aureus, E. coli, and P. aeruginosa. MDP1 acetate is used in antimicrobial membrane biology research systems to investigate peptide-induced membrane disruption, bacterial permeability changes, and antimicrobial peptide mechanism profiling. |
| In vivo | Method: MDR Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were treated with melittin-derived peptides MDP1 and MDP2. Antibacterial activity was assessed along with DNA release, calcein release, flow cytometry, and SEM analysis of membrane damage. Result: MDP1 and MDP2 showed high antibacterial activity against MDR and reference bacterial strains. Both peptides induced time-dependent DNA and calcein release, and flow cytometry indicated time-dependent antibacterial effects. SEM showed dose- and time-dependent vesicle formation, pore formation, and cell lysis in S. aureus and E. coli. The peptides disrupted bacterial membrane integrity and killed bacteria via membrane damage. |
| Molecular Weight | 2521.05 |
| Formula | C113H206N34O30 |
| Sequence | Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Lys-Arg-Lys-Arg-Gln-Gln |
| Sequence Short | GIGAVLKVLTTGLPALIKRKRQQ |
| Storage | Keep away from moisture,Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: MDP1 acetate chemical structure | MDP1 acetate in vivo | MDP1 acetate formula | MDP1 acetate molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.