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Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2
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Catalog No. TMAC-03813
Alias SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-03813Alias SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in IF,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in IF,WB. |
| Synonyms | SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of extracts from HT29 cells using SNAI1 (Phospho-Ser246) Antibody TMAC-03813. The lane on the right is treated with the antigen-specific peptide. 2. Immunofluorescence staining of methanol-fixed HuvEc cells using SNAI1 (Phospho-Ser246) Antibody TMAC-03813.   |
| Application | |
| Recommended Dose | WB: 1:500-1000; IF: 1:100-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 246(T-F-S(p)-R-M) derived from Human SNAI1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 29 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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