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NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune checkpoint inhibitors.It is expressed only in NK-cells, but not in T-cells or B-cells. NKG2A/CD159a Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.3 kDa and the accession number is P26715-1.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $91 | 7-10 days | |
| 10 μg | $148 | 7-10 days | |
| 20 μg | $245 | 7-10 days | |
| 50 μg | $483 | 7-10 days | |
| 100 μg | $813 | 7-10 days | |
| 200 μg | $1,470 | 7-10 days | |
| 500 μg | $3,250 | 7-10 days |
| Biological Activity | Immobilized Anti-NKG2A Antibody, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human NKG2A, His Tag with the EC50 of 0.27μg/ml determined by ELISA. |
| Description | NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune checkpoint inhibitors.It is expressed only in NK-cells, but not in T-cells or B-cells. NKG2A/CD159a Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.3 kDa and the accession number is P26715-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-His-Avi |
| Accession Number | P26715-1 |
| Synonyms | NKG2-A,NKG2A,KP43,KLRD1,KLRC1,CD94,CD159A |
| Construction | Arg100-Leu233 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Molecular Weight | 18.3 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. |
| Research Background | NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune checkpoint inhibitors.It is expressed only in NK-cells, but not in T-cells or B-cells. |

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