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RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)

Catalog No. TMPJ-01472

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-29 KDa and the accession number is O35235-1.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
Pack Size Availability Price/USD Quantity
10 μg Inquiry $ 260.00
50 μg Inquiry $ 913.00
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Biological Description
Technical Params
Product Properties
Description RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-29 KDa and the accession number is O35235-1.
Species Mouse
Expression System HEK293 Cells
Tag N-6xHis-Flag
Accession Number O35235-1
Amino Acid Lys158-Asp316
Construction Lys158-Asp316
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 23-29 KDa (reducing condition)
Endotoxin < 0.01 EU/μg of the protein as determined by the LAL method.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM His-HCl, 100 mM NaCl, 10% Trehalose, 0.05% Tween 80, pH5.5.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.

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Keywords

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