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Synonyms: TRPM-2, Testosterone-Repressed Prostate Message 2, NA1/NA2, KUB1, Ku70-Binding Protein 1, Complement-Associated Protein SP-40, Complement Cytolysis Inhibitor, Clusterin, CLU, CLI, Apolipoprotein J, Apo-J, APOJ, Aging-Associated Gene 4 Protein, AAG4, 40

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $61 | 7-10 days | 7-10 days | |
| 10 µg | $97 | 7-10 days | 7-10 days | |
| 20 µg | $148 | 7-10 days | 7-10 days | |
| 50 µg | $272 | 7-10 days | 7-10 days | |
| 100 µg | $485 | 7-10 days | 7-10 days | |
| 200 µg | $869 | 7-10 days | 7-10 days | |
| 500 µg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human Clusterin, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Clusterin Antibody, hFc Tag with the EC50 of 9.0 ng/ml determined by ELISA (QC Test). |
| Description | Clusterin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-40 KDa and the accession number is P10909. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P10909-1 |
| Amino Acid | Asp23-Glu449 |
| Construction | Asp23-Glu449 |
| Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TRPM-2, Testosterone-Repressed Prostate Message 2, NA1/NA2, KUB1, Ku70-Binding Protein 1, Complement-Associated Protein SP-40, Complement Cytolysis Inhibitor, Clusterin, CLU, CLI, Apolipoprotein J, Apo-J, APOJ, Aging-Associated Gene 4 Protein, AAG4, 40 |
| Research Background | Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others. |
| Molecular Weight | 38-41 kDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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