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MINPP1 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01390
Synonyms: 3, 4, 5)-Tetrakisphosphate 3-Phosphatase, 2, 5)P(4) 3-Phosphatase, 3-BPG Phosphatase, Multiple Inositol Polyphosphate Phosphatase 1, 3-Bisphosphoglycerate 3-Phosphatase, MINPP1, Ins(1, Inositol (1, MIPP

Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).

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MINPP1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 129.00
50 μg 5 days $ 390.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
Species Human
Expression System Human Cells
Tag C-6His
Accession Number Q9UNW1
Synonyms 3, 4, 5)-Tetrakisphosphate 3-Phosphatase, 2, 5)P(4) 3-Phosphatase, 3-BPG Phosphatase, Multiple Inositol Polyphosphate Phosphatase 1, 3-Bisphosphoglycerate 3-Phosphatase, MINPP1, Ins(1, Inositol (1, MIPP
Amino Acid Ser31-Leu487
Construction Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 56 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).

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Keywords

MINPP1 Protein, Human, Recombinant (His) 3 4 5)-Tetrakisphosphate 3-Phosphatase 2 5)P(4) 3-Phosphatase 3-BPG Phosphatase Multiple Inositol Polyphosphate Phosphatase 1 MINPP 1 MINPP-1 3-Bisphosphoglycerate 3-Phosphatase MINPP1 Ins(1 Inositol (1 MIPP recombinant recombinant-proteins proteins protein

 

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