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Anti-Phospho-Src (Tyr530) Antibody (5Q242)
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Catalog No. TMAY-01694
Alias THC6, SRC1, p60-Src, c-SRC, ASV
Anti-Phospho-Src (Tyr530) Antibody (5Q242) is a Rabbit antibody targeting Phospho-Src (Tyr530). Anti-Phospho-Src (Tyr530) Antibody (5Q242) can be used in WB.
Anti-Phospho-Src (Tyr530) Antibody (5Q242)
Anti-Phospho-Src (Tyr530) Antibody (5Q242)
😃Good
Catalog No. TMAY-01694Alias THC6, SRC1, p60-Src, c-SRC, ASV
Anti-Phospho-Src (Tyr530) Antibody (5Q242) is a Rabbit antibody targeting Phospho-Src (Tyr530). Anti-Phospho-Src (Tyr530) Antibody (5Q242) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $82 | 7-10 days | |
| 100 μL | $233 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Src (Tyr530) Antibody (5Q242) is a Rabbit antibody targeting Phospho-Src (Tyr530). Anti-Phospho-Src (Tyr530) Antibody (5Q242) can be used in WB. |
| Alias | THC6, SRC1, p60-Src, c-SRC, ASV |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5Q242 |
| Reactivity | Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Chicken, Zebrafish |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved Jurkat, untreated(line A) or treated with H2O2(2mM, 2min; +)(line B), using Phospho-Src (Tyr530) rabbit monoclonal Antibody at 1:2000 dilution (upper) or Anti-Actin Antibody, Chimeric Rabbit Monoclonal at 1:50000 dilution (lower). 2. Western blot analysis of extracts from serum-starved Jurkat, untreated (line A); treated with H2O2(2mM, 2min; +) (line B); treated with H2O2and λ-phosphatase (line C) using Phospho-Src (Tyr530) rabbit monoclonal Antibody at 1:2000 dilution. (Validation Experiment) 3. Western blot analysis of extracts from serum-starved Jurkat treated with H2O2(2mM, 2min), using Phospho-Src (Tyr530) rabbit monoclonal Antibody at 1:10000, 1:50000, 1:200000 dilution. (Validation Experiment) |
| Application | WB |
| Recommended Dose | WB: 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around (Tyr530) of Human Phospho-Src. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the residues around (Tyr530) of Human Phospho-Src |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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